Update on Direct Oral Anticoagulants in the Emergency Department

Authors: Megan Donohue MD, MPH, Erica Bates MD, Robert Brown MD, Christine Carter MD, Hannah Goldberg MD.
Editors: Kami M. Hu MD FAAEM, Kelly Maurelus, MD FAAEM
Originally Published: Common Sense May/June 2018

Questions: What new information do we have regarding direct oral anticoagulants (DOACs), specifically:

1. What is the most recent safety data?
2. Do our standard coagulation assays provide an accurate measure of anticoagulant activity?
3. Where do we stand with reversal agents?