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Author: Jonathan Morgan, MSIV Lake Erie College of Osteopathic Medicine-Bradenton
Case:
EMS calls; they are 5 minutes out
with a 50-year-old female patient in cardiac arrest with massive airway bleeding. She began coughing up blood and collapsed several minutes prior to EMS arrival. She is currently intubated with a 7.0 ETT, 3 doses of epinephrine have been administered, and CPR is ongoing; she has been alternating between
PEA and asystole. Family reported a recent diagnosis of lung cancer.
What defines massive hemoptysis?
There is no consensus on the definition of “massive.” Many sources use a definition of
600cc of expectorated blood per hour, but proposed cutoffs run between 200 and 1000 mL/hr. [1] However, estimating blood volumes can be difficult and it may only take 100-400mL of blood in the airway to cause impaired gas exchange.[1,2] Because of this, some proposals call for inclusion of other clinical data including
evidence of impaired gas exchange or hemodynamic derangements to define “massive.”[3]
What is the likely etiology of this patient’s cardiovascular collapse?
Asphyxiation rather than exsanguination is the most likely cause of cardiovascular collapse in massive hemoptysis.[4] 90% of cases of massive hemoptysis are caused by bleeding in the bronchial circulation, which is exposed to systemic pressures; bleeding in the low pressure pulmonary circulation accounts for only 5% of cases.[2]